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Demonstrates that Enterovirus 71 was circulating widely in Cambodia long before the recognized 2012 outbreak.
Enterovirus 71 is reported to have emerged in Cambodia in 2012; at least 54 children with severe encephalitis died during that outbreak. We used serum samples collected during 2000-2011 to show that the virus had been widespread in the country for at least a decade before the 2012 outbreak.
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Horwood et al. (2015) studied this question.
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