Population
Cultured single cells isolated from rat portal vein
Design
Preclinical
Authors
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Findings in rat portal vein cells should not change practice; extends preclinical alpha1-adrenoceptor mechanisms but leaves open human translation.
Noradrenaline induces depolarization in rat portal vein cells by increasing chloride conductance via intracellular calcium release and enhancing voltage-dependent calcium currents.
Pacaud et al. (1989) studied this question.
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