Population
Perfused isolated rabbit ear artery model
Comparison
Exogenous norepinephrine introduced exclusively… vs Endogenous norepinephrine released from…
Design
Preclinical
Authors
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Benchmarks perivascular norepinephrine in isolated arteries; extends sympathetic neurotransmission models but leaves open human translation.
The relative sensitivity of the rabbit ear artery to endogenous and exogenous norepinephrine is similar, with local factors affecting concentrations reaching the smooth muscle to a similar degree.
J. G. Waterson (1973) studied this question.
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