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June 1, 2001The Journal of ImmunologyOpen Access

PU.1 and Multiple IFN Regulatory Factor Proteins Synergize to Mediate Transcriptional Activation of the Human IL-1β Gene

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SMSylvia MareckiBoston Medical CenterCRCarrie J. RiendeauUniversity of Massachusetts Chan Medical SchoolMLMichael D. LiangBoston University

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Marecki et al. (2001) studied this question.

synapsesocial.com/papers/6a8d1df2174c4b1ddccf8a08https://doi.org/10.4049/jimmunol.166.11.6829
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1NFκB and Interferon Regulatory Factor 1 Physically Interact and Synergistically Induce Major Histocompatibility Class I Gene Expression1995 · 123 citations
  2. 2Interferon consensus sequence-binding protein, a member of the interferon regulatory factor family, suppresses interferon-induced gene transcription.1993 · 188 citations
  3. 3IL-1 expression in human monocytes is transcriptionally and posttranscriptionally regulated by IL-41991 · 102 citations
  4. 4PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.1992 · 358 citations
  5. 5Interaction of interferon regulatory factor-1 and nuclear factor κB during activation of inducible nitric oxide synthase transcription1999 · 163 citations