Why the study?
Much controversy exists regarding the optimal use of aspirin in pregnancy, with guidelines across global organizations varying.
This narrative review summarizes current literature and guidelines regarding the optimal dose, timing, duration, and safety of aspirin for preeclampsia prevention in high-risk pregnancies.
Highlights ongoing uncertainty regarding optimal aspirin dosing and timing for preeclampsia prevention; leaves open the need for.
Preeclampsia is associated with significant perinatal morbidity and mortality. Aspirin has been long purported and extensively studied for prevention of preeclampsia. For this reason, the U.S. Preventive Services Task Force, the American College of Obstetricians and Gynecologists, and the Society for Maternal-Fetal Medicine recommend its use in pregnancy for preeclampsia prevention in those at high risk. Yet, much controversy exists regarding optimal use in pregnancy with guidelines across global organizations varying. In this narrative review, we summarize the published literature related to the safety, optimal dose, and timing and duration of use of aspirin, as well as other indications for which aspirin has been studied in pregnancy.
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Boggess et al. (2023) studied this question.
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