Why the study?
The Wnt pathway is altered in patients with T2DM and plays an important role in vascular pathophysiology, but a concise synthesis of how altered Wnt pathway molecules contribute to micro- and macrovascular complications is needed to highlight potential therapeutic strategies.
The Wnt signaling pathway is a key contributor to endothelial dysfunction and vascular complications in T2DM, representing a potential therapeutic target.
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Torre et al. (2022) studied this question.
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