Radiomodifying effects of the root extract of Panax ginseng were observed on the testes of Swiss albino mice at 10 and 20 mg/kg dose. The root extract was found to be non-toxic when injected up to 1200 mg/kg. A significant enhancement was observed in the survival time of the irradiated group compared with the control when pretreated with ginseng extract. Besides survival time, radiation induced damage to the germ cells and loss of body weight were also reduced markedly by this treatment. The probable reason for this radioprotection can be correlated with the increased level of liver glutathione (GSH).
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Pande et al. (1998) studied this question.