July 1, 1970Archives of Internal Medicine
Induction of Interferon by Nonviral Agents
Population
cells and experimental viral infection models
Design
Review
Authors
Discussion
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Member takes
Implication
Does not support clinical use of nonviral interferon inducers; leaves open their mechanistic exploration in contemporary antiviral research.
Structured PICO
P
Population
cells and experimental viral infection models
I
Intervention
Nonviral agents (nonviral nucleic acids, bacteria, mold products like statolon and helenine)
O
Outcome
Interferon production
Provides a historical overview of the discovery that nonviral agents can induce interferon production.
Cite This Study
Erik De Clercq (1970) studied this question.