January 1, 1999Chemical Communications

Synthesis and study of an acridine substituted Tröger’s base: preferential binding of the (–)-isomer to B-DNA

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Abstract

The acridine substituted Tröger’s base 4 was prepared, resolved and the (–)-(7R,17R) enantiomer was shown to bind preferentially to calf-thymus B-DNA.

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Tatibouët et al. (1999) studied this question.

synapsesocial.com/papers/6a8d25c8e2934571205be629 https://doi.org/10.1039/a808822e

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Abstract

The acridine substituted Tröger’s base 4 was prepared, resolved and the (–)-(7R,17R) enantiomer was shown to bind preferentially to calf-thymus B-DNA.

Synthesis and study of an acridine substituted Tröger’s base: preferential binding of the (–)-isomer to B-DNA

Abstract

Discussion

Cite This Study

Synthesis and study of an acridine substituted Tröger’s base: preferential binding of the (–)-isomer to B-DNA

Abstract

Discussion

Cite This Study

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