Mutual Effects of Diabetes, Obesity and Sars-Cov-2

Since the first outbreak of SARS-Cov-2 in China, much attention has been paid by the medical community to people with diabetes, as it is well known that diabetes increases the risk of developing various infectious diseases. The reason for this is multifactorial: age, gender, ethnicity, concomitant diseases such as hypertension and cardiovascular diseases, obesity, as well as pro-inflammatory and procoagulatory conditions – all these factors contribute to a more severe course of SARS-Cov-2 in patients with diabetes mellitus. Moreover, severe SARS-Cov-2 infection itself may be a worsening factor for people with diabetes, as it can cause acute metabolic complications through direct negative effects on beta-cell function. This review is intended to provide a systematic assessment of potential prognostic factors and mutual effects in patients with diabetes mellitus, obesity and SARS-Cov-2.