Indomethacin-Induced Inhibition of Prostaglandin with Hyperkalemia

Letters1 September 1979Indomethacin-Induced Inhibition of Prostaglandin with HyperkalemiaVINCENT BERONIADE, M.D., D.SC., LOUISE CORNEILLE, M.D., BOULOS HARAOUI, M.D.VINCENT BERONIADE, M.D., D.SC.Search for more papers by this author, LOUISE CORNEILLE, M.D.Search for more papers by this author, BOULOS HARAOUI, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-91-3-499_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptTo the editor: When the article by Tan and associates (1) appeared in the May 1979 issue, we had just seen a similar case.An 82-year-old woman was receiving 25 mg of indomethacin four times a day and 10 grains of acetylsalicylic acid (aspirin) four times a day for rheumatoid arthritis. She had just developed an isoniazid polyneuritis and was on rifampicin-ethambutol therapy for active pulmonary tuberculosis. High blood pressure and edema secondary to indomethacin were controlled with furosemide, 40 mg daily. Renal function deterioration and hyperkalemia (highest value, 7.4 meq/L) resistant to sodium polystryrene sulfonate (Kayexalate; Winthrop Laboratories, New...References1. TANSHAPIROFRANCOSTOCKARDMULROW SRRHP. Indomethacin-induced prostaglandin inhibition with hyperkalemia: a reversible cause of hyporeninemic hypoaldosteronism. Ann Intern Med. 1979;90:783-5. LinkGoogle Scholar2. THURAUSCHNERMANNNAGELHORSTERWAHI KJWMM. Composition of tubular fluid in the macula densa segment as a factor regulating the function of the juxtaglomerular apparatus. Circ Res. 1967;20-21:(suppl. 2):79-90. Google Scholar3. BERONIADEANTONESCU VC. Functional interpretations of some abnormalities occuring in the minute-sequence urography. In: IV-th International Congress on Nephrology. Vol. 1. Stockholm: International Congress on Nephrology; 1969:407. Abstract. Google Scholar1. TANSHAPIROFRANCOSTOCKARDMULROW SRRHP. Indomethacin-induced prostaglandin inhibition with hyperkalemia: a reversible cause of hyporeninemic hypoaldosteronism. Ann Intern Med. 1979; 90:783-5. LinkGoogle Scholar2. MACCARTHYFROSTSTOKES EGG. Indomethacin-induced hyperkalemia. Med J Aust. 1979; 1:550. CrossrefMedlineGoogle Scholar3. KIMBERLYBOWDENKEISERPLOTZ RRHP. Reduction of renal function by newer nonsteroidal antiinflammatory drugs. Am J Med. 1978; 64:804-7. CrossrefMedlineGoogle Scholar4. WIDSTRÖOM A. Influence of indomethacin on glucose-induced insulin response in normal man: Role of prostaglandins in rapid insulin release? Horm Metab Res. 1977; 9:172-5. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: University of Montreal HÔtel-Dieu de Montréal Montreal Canada PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByHyperkalemia in the elderlyPotassium Homeostasis With Indomethacin Therapy in Normal SubjectsAnalgesic Nephropathy and the Effect of Non-Steroidal Anti-Inflammatory Drugs on the KidneyCardiac arrest secondary to indomethacin-induced renal failure: A case reportToxic NephropathiesRenal Side Effects of Nonsteroidal Antiinflammatory Drugs: Clinical RelevanceEffects of acute and chronic dosing of NSAIDs in patients with renal insufficiencySerum electrolyte abnormalities caused by drugsIncidence of hyperkalaemia induced by indomethacin in a hospital population.Renal Syndromes Associated with Nonsteroidal Antiinflammatory DrugsAccidents néphrologiques des anti-inflammatoires non stéroïdiensIndomethacin-Associated Hyperkalemia in the ElderlyOur national obsession with potassium 1 September 1979Volume 91, Issue 3Page: 499-500KeywordsAspirinEdemaIsoniazidPrimary hypertensionProstaglandinRheumatoid arthritisSodium Issue Published: 1 September 1979 PDF DownloadLoading ...