Why the study?
Cilostazol is used in Asia-Pacific countries for stroke prevention but rarely elsewhere, despite laboratory models showing vascular and neural effects that may prevent small vessel disease progression.
Does cilostazol reduce recurrent stroke and cognitive decline in patients requiring secondary stroke prevention?
Does cilostazol reduce recurrent stroke and cognitive decline in patients requiring secondary stroke prevention?
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Cilostazol appears effective for long-term secondary stroke prevention without increasing hemorrhage risk, particularly in lacunar stroke, though it increases headache and palpitations.
McHutchison et al. (2020) studied this question.
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