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Three chromene meroterpenoids ( 1 , 3 , and 4 ), were isolated from Rhododendron anthopogonoides . These meroterpenoids possess a benzo‐α‐pyran core and a linear terpene side chain. Their chemical structures were established by high‐resolution electrospray ionization mass spectrometry and comprehensive spectroscopic analysis. The structures of 2 and 3 , C‐7'/C‐8' double‐bond isomers, were confirmed by DP4+ analysis via comparison of experimental and calculated NMR chemical shifts, allowing for the revision of the incorrectly assigned configuration of 2 . The stereochemistry of the chiral hydroxyls at C‐6', C‐7', and C‐10' in 4 were determined using Mo 2 (OAc) 4 ‐induced electronic circular dichroism spectra, combined with NMR chemical shift calculations. These compounds exhibited weak inhibitory activity against nitric oxide (NO) production in LPS‑stimulated RAW264.7 cells.
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Chen et al. (2026) studied this question.
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