Why the study?
The clinical characteristics and therapeutic distinctiveness of the recently introduced HFmrEF phenotype are not yet well understood.
What are the clinical characteristics and correlates of heart failure with mid-range ejection fraction (HFmrEF) compared to HFpEF and HFrEF in southwest Nigeria?
Comparison
HFmrEF vs HFpEF vs HFrEF
Design
Two-centre observational study
Key result
Heart failure with mid-range ejection fraction (HFmrEF) accounted for 27.5% of the cohort and exhibited clinical characteristics intermediate between HFpEF (29.0%) and HFrEF (43.5%).
Authors
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Supports managing HFmrEF as a distinct transitional phenotype rather than a strict HFrEF or HFp.
Cross-Sectional (n=269)
Yes
What are the clinical characteristics and correlates of heart failure with mid-range ejection fraction (HFmrEF) compared to HFpEF and HFrEF in southwest Nigeria?
In a Nigerian cohort, HFmrEF accounts for 27.5% of heart failure cases and presents with clinical characteristics intermediate between HFpEF and HFrEF.
Adeseye A. Akintunde (2021) conducted a cross-sectional in Heart Failure (n=269). Heart failure with mid-range ejection fraction (HFmrEF) vs. Heart failure with preserved (HFpEF) or reduced (HFrEF) ejection fraction was evaluated on Prevalence and clinical characteristics of HF phenotypes. Heart failure with mid-range ejection fraction (HFmrEF) accounted for 27.5% of the cohort and exhibited clinical characteristics intermediate between HFpEF (29.0%) and HFrEF (43.5%).