Key result
Exercise stress echocardiography on a horizontal bicycle ergometer demonstrated 70% sensitivity, 93% specificity, and 86% overall accuracy for detecting anatomically significant coronary artery stenoses in patients with low-risk NSTE-ACS.
Why the study?
The diagnostic accuracy of exercise stress echocardiography on a horizontal bicycle ergometer for detecting obstructive CAD in low-risk NSTE-ACS was evaluated.
Does exercise stress echocardiography on a horizontal bicycle ergometer accurately detect obstructive coronary artery disease in patients with low-risk NSTE-ACS?
Observational (n=95)
No
Does exercise stress echocardiography on a horizontal bicycle ergometer accurately detect obstructive coronary artery disease in patients with low-risk NSTE-ACS?
Odds Ratio: 30.1 (95% CI 4.9–186.5)
Exercise stress echocardiography on a horizontal bicycle ergometer is a safe and highly specific non-invasive tool for identifying anatomically significant coronary artery disease in low-risk NSTE-ACS patients.
Supports the feasibility of stress echocardiography for risk-stratifying low-risk NSTE-ACS;.
Objective. To evaluate the diagnostic accuracy of exercise stress echocardiography(EchoCG) on a horizontal bicycle ergometer for the detection of obstructive coronary heart disease(oCAD) in patients with low-risk non-ST-segment elevation acute coronary syndrome(NSTEACS). Material and methods. The study included 95 patients, mean age 53 years, 58% of men hospitalized in the department of the regional vascular center with a diagnosis of NSTE-ACS were at low risk. Patients with known coronary heart disease and impaired left ventricular contractility at rest were not included. They underwent stress echocardiography on a horizontal bicycle ergometer according to standard methods of conduct and interpretation, and invasive or non-invasive coronary angiography(CAG). All values of coronary obstruction ≥70% were verified by invasive coronary angiography. The assessment of myocardial revascularization was observational in nature. Results. The result of stress echocardiography according to the criterion of impaired local contractility(ILC) was positive in 16%, negative in 28%, incomplete symptom-limited in 35% patients. Coronary artery stenosis ≥50%/≥70% was detected in 78/78% of cases in the subgroup with a positive result, in 29/11% with a negative result, 30/10% with a non-diagnostic result. The association of NLS with stenosis ≥70% was higher odds ratio 30.1vs8.5 for stenoses ≥50%. Conclusion Stress echocardiography with exercise on a horizontal bicycle ergometer in patients with low-risk NSTE-ACS is safe and feasible. The method has moderate sensitivity and high specificity and overall accuracy for identifying anatomically significant coronary artery stenoses.
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Lobo et al. (2023) conducted an observational in Low-risk non-ST-segment elevation acute coronary syndrome (NSTE-ACS) (n=95). Exercise stress echocardiography on a horizontal bicycle ergometer vs. Coronary angiography was evaluated on Detection of coronary artery stenosis ≥70% (OR 30.1, 95% CI 4.9-186.5). Exercise stress echocardiography on a horizontal bicycle ergometer demonstrated 70% sensitivity, 93% specificity, and 86% overall accuracy for detecting anatomically significant coronary artery stenoses in patients with low-risk NSTE-ACS.
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