Cohort study reveals a 43% five-year survival rate in cutaneous melanoma, highlighting tumor size, ulceration, and lymph node involvement as critical prognostic markers.
A study of 49 patients with malignant melanoma of the skin occurring over an 18-year period is presented. The over-all 5-year survival was 43%. The prognosis was uniformly better for females and for lesions less than one cm. A poor prognosis was associated with primary lesions on the trunk, ulceration or hemorrhage of the primary and clinically and microscopically positive nodes. The authors conclude that a wide local excision of the primary lesion, including a 3 to 5 cm margin of skin, combined with an in-continuity regional lymph node dissection should be the treatment of choice.
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Lehman et al. (1966) studied this question.
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