A novel approach to chiral succinimides and derived compounds has been developed that involves chiral lithium amide desymmetrisation of an N-ortho-tert-butylphenyl succinimide to generate a putative atropisomeric intermediate enolate, alkylation of which enables access to the lignan lactone (+)-hinokinin.
No takes yet. Share an insight, caveat, or question.
Bennett et al. (2004) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: