Key result
Non-cardiac chest pain had similar 4-year cardiac mortality compared to cardiac chest pain (5.5% vs 11%, P=0.16), but higher rates of continued chest pain at 2 years (90% vs 69%, P<0.001).
Why the study?
Does non-cardiac chest pain confer a different long-term prognosis compared to cardiac chest pain in patients presenting to the emergency department?
Cohort (n=197)
No
Does non-cardiac chest pain confer a different long-term prognosis compared to cardiac chest pain in patients presenting to the emergency department?
Absolute Event Rate: 5.5% vs 11%
p-value: p=0.16
Non-cardiac chest pain does not always confer an excellent long-term prognosis, as mortality rates did not significantly differ from those with cardiac chest pain over 4 years, and the majority of patients continued to experience symptoms.
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Non-cardiac chest pain may warrant symptom-focused follow-up despite comparable mortality; leaves open optimal risk stratification in ED cohorts.
Eslick et al. (2008) conducted a cohort in Acute chest pain (n=197). Non-cardiac chest pain vs. Cardiac chest pain was evaluated on Cardiac mortality at 4 years (p=0.16). Non-cardiac chest pain had similar 4-year cardiac mortality compared to cardiac chest pain (5.5% vs 11%, P=0.16), but higher rates of continued chest pain at 2 years (90% vs 69%, P<0.001).
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