Key result
Combined carotid endarterectomy and coronary artery bypass grafting resulted in a permanent stroke rate of 2.6% and a mortality rate of 5%.
Observational (n=40)
Combined CEA and CABG in high-risk patients can be performed with a permanent stroke rate comparable to either procedure alone and a 5% mortality rate.
May support combined CEA-CABG in selected patients; leaves open need for randomized comparisons to staged approaches.
A retrospective review of 40 consecutive patients undergoing combined coronary artery bypass grafting (CABG) and unilateral carotid endarterectomy (CEA) was carried out to determine the stroke rate for the procedure. Patients presenting with severe coronary artery disease judged to be at risk of imminent myocardial infarction, who had signs of cerebral ischaemia (70%) or asymptomatic carotid bruits (30%), were investigated for extracranial carotid vascular disease. Patients with severe stenotic carotid lesions associated with high risk coronary artery disease underwent combined CEA/CABG. Three patients had a previous contralateral CEA. The average age of the patients was 62 years, and there were 31 males and nine females. CEA was completed prior to CABG under the same general anaesthetic. There were 24 CEAs on the left and 16 on the right. Six patients suffered a postoperative cerebral ischaemic event (15.4%): a reversible ischaemic neurological deficit in three (7.7%), a transient ischaemic cerebral event in two (5.1%), and a permanent stroke occurred in one (2.6%). Two deaths occurred and both were cardiac related. Combined CEA/CABG in patients with stenotic lesions of the coronary and extra-cranial carotid vascular systems who are at risk of cerebral or myocardial infarction, can be performed with a permanent stroke rate within the published range for either CEA or CABG alone and with a mortality of 5%.
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Lubicz et al. (1987) conducted an observational in Severe coronary artery disease and severe stenotic carotid lesions (n=40). Combined coronary artery bypass grafting (CABG) and unilateral carotid endarterectomy (CEA) was evaluated on Permanent stroke. Combined carotid endarterectomy and coronary artery bypass grafting resulted in a permanent stroke rate of 2.6% and a mortality rate of 5%.
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