Key result
The CAD-RADS score significantly improved risk stratification for early major adverse cardiac events over clinical risk factors alone (C-index 0.901 vs 0.814; P<0.05).
Why the study?
The study aimed to compare the prognostic performance of the CAD-RADS score with clinical risk factors and extent of CAD classification for predicting major adverse cardiac events in emergency department patients.
Does the CAD-RADS score improve prediction of major adverse cardiac events compared to clinical risk factors in emergency department patients with acute chest pain?
Observational (n=779)
Does the CAD-RADS score improve prediction of major adverse cardiac events compared to clinical risk factors in emergency department patients with acute chest pain?
The CAD-RADS score derived from cardiac CT angiography provides additional prognostic value over clinical risk factors for predicting major adverse cardiac events in ED patients with acute chest pain.
Answers are grounded in this paper and cite their sources.
Supports using CAD-RADS for risk stratification in acute chest pain; leaves open whether.
OBJECTIVE: This study aimed to compare the prognostic performance of Coronary Artery Disease (CAD)-Reporting and Data System (CAD-RADS) score with those of clinical risk factors and the extent of CAD classification for predicting major adverse cardiac events in emergency department patients. METHODS: A total of 779 patients with acute chest pain at low to intermediate risk for CAD underwent cardiac computed tomography angiography. The primary end point was early and late major adverse cardiac events. We developed the following models: model 1, clinical risk factors; model 2, clinical risk factors and CAD-RADS scores; model 3, clinical risk factors and extent of CAD. RESULTS: The C-statistics revealed that both CAD-RADS score and CAD extent improved risk stratification over the clinical risk factors (C-index for early events: C-index: 0.901 vs 0.814 and 0.911 vs 0.814; C-index for late events: 0.897 vs 0.808 and 0.905 vs 0.808; all P < 0.05). CONCLUSIONS: The CAD-RADS score had additional risk prediction benefits over clinical risk factors for emergency department patients.
No takes yet. Share an insight, caveat, or question.
Park et al. (2021) conducted an observational in acute chest pain (n=779). CAD-RADS score vs. clinical risk factors was evaluated on early and late major adverse cardiac events (C-index 0.901 vs 0.814 (early) and 0.897 vs 0.808 (late), p=< 0.05). The CAD-RADS score significantly improved risk stratification for early major adverse cardiac events over clinical risk factors alone (C-index 0.901 vs 0.814; P<0.05).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: