Key result
Adding right coronary artery PCAT CT attenuation to CAD-RADS fails to improve MACE risk stratification.
Why the study?
The comparative prognostic value of pericoronary adipose tissue CT attenuation and CAD-RADS for predicting major adverse cardiovascular events in acute chest pain patients was unclear.
Does the addition of right coronary artery PCAT CT attenuation to CAD-RADS improve prognostic prediction for MACEs in emergency patients with acute chest pain?
Population
1313 consecutive emergency patients with acute chest pain referred for coronary computed tomography angiography
Comparison
Right coronary artery PCAT CT attenuation combined with CAD-RADS vs CAD-RADS alone
Design
Retrospective cohort study
Follow-up
Median 38 months
Authors
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Does not support adding right coronary PCAT attenuation to CAD-RADS for MACE prediction in acute chest pain; leaves open its value in other cohorts or endpoints.
Cohort (n=1,313)
Does the addition of right coronary artery PCAT CT attenuation to CAD-RADS improve prognostic prediction for MACEs in emergency patients with acute chest pain?
p-value: p=0.129
Right coronary artery PCAT CT attenuation does not provide incremental prognostic value beyond CAD-RADS for predicting MACEs in patients presenting with acute chest pain.
Wen et al. (2023) conducted a cohort in Acute chest pain (n=1,313). Right coronary artery PCAT CT attenuation combined with CAD-RADS vs. CAD-RADS alone was evaluated on Major adverse cardiovascular events (unstable angina requiring hospitalization, coronary revascularization, nonfatal myocardial infarction, and all-cause death) (p=0.129). Right coronary artery PCAT CT attenuation combined with CAD-RADS did not significantly improve risk stratification for MACEs compared with CAD-RADS alone (C-index 0.777 vs 0.760; P=0.129).
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