Key result
Argonaute proteins interact with GW182 proteins to mediate the downstream steps of small RNA-guided gene silencing.
Design
Review
Authors
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May inform RNA-based interventions; leaves open validation in cardiovascular models.
This review provides an overview of the molecular mechanisms underlying Argonaute-GW182 protein interactions in gene silencing.
Pfaff et al. (2013) conducted a review in Gene silencing. Argonaute-GW182 protein interactions was evaluated. Argonaute proteins interact with GW182 proteins to mediate the downstream steps of small RNA-guided gene silencing.
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