Key result
Significant coronary artery disease was an independent risk factor for postoperative advanced acute kidney injury (OR 1.798; 95% CI 1.094-2.955) in patients undergoing valvular heart surgery.
Why the study?
The impact of nonsignificant coronary artery disease on postoperative outcomes in patients undergoing valvular heart surgery is not well understood.
Does concomitant coronary artery disease impact postoperative acute kidney injury, ICU stay, and mortality in adult patients undergoing valvular heart surgery?
Case-Control (n=4,172)
No
Does concomitant coronary artery disease impact postoperative acute kidney injury, ICU stay, and mortality in adult patients undergoing valvular heart surgery?
Odds Ratio: 1.798 (95% CI 1.094–2.955)
Concomitant moderate and significant CAD are independent risk factors for postoperative advanced AKI in patients undergoing valvular heart surgery.
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Identifies coronary artery disease as a preoperative marker for advanced acute kidney injury risk.
Xie et al. (2019) conducted a case-control in Valvular heart surgery with concomitant coronary artery disease (n=4,172). Coronary artery disease vs. No or non-significant coronary artery disease was evaluated on Postoperative advanced acute kidney injury (grade 2 or 3 by KDIGO criteria) (OR 1.798, 95% CI 1.094-2.955). Significant coronary artery disease was an independent risk factor for postoperative advanced acute kidney injury (OR 1.798; 95% CI 1.094-2.955) in patients undergoing valvular heart surgery.
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