Key result
Mitral annular calcification in patients aged ≤ 65 years was associated with a significantly higher prevalence of severe coronary artery disease compared to those without (88% vs 68%, p=0.0004).
Why the study?
Does the presence of mitral annular calcification on echocardiography predict severe coronary artery disease in patients aged ≤ 65 years?
Population
221 patients aged ≤ 65 years who underwent coronary angiography within one year of their qualifying…
Comparison
Presence of mitral annular calcification… vs Absence of mitral annular calcification
Design
Case-control
Authors
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May flag higher CAD risk on echo in patients ≤65 years; leaves open whether it should alter screening or management.
Observational (n=221)
Does the presence of mitral annular calcification on echocardiography predict severe coronary artery disease in patients aged ≤ 65 years?
Absolute Event Rate: 88% vs 68%
p-value: p=0.0004
In patients aged 65 years or younger, the presence of mitral annular calcification on echocardiography is a strong marker for severe obstructive coronary artery disease.
Shaul Atar (2003) conducted an observational in Coronary artery disease (n=221). Mitral annular calcification vs. Without mitral annular calcification was evaluated on Severe coronary artery disease (≥ 70% stenosis of at least one major epicardial coronary artery) (p=0.0004). Mitral annular calcification in patients aged ≤ 65 years was associated with a significantly higher prevalence of severe coronary artery disease compared to those without (88% vs 68%, p=0.0004).
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