Key result
Mitral annular calcification predominantly affects females over 65, driving MR managed with medical therapy.
Why the study?
Mitral annular calcification predominantly affects females over 65 and requires clear diagnostic and management guidance.
Mitral annular calcification is a condition predominantly affecting older females, diagnosed via echocardiography, and managed with endocarditis prophylaxis and heart failure therapies if needed.
Supports endocarditis prophylaxis in older women with mitral regurgitation; leaves open prospective trials to refine management strategies.
Mitral annular calcification is predominantly a disease of females, typically above 65 years of age. The diagnosis should be considered in patients with a systolic murmur which is mitral in origin. This murmur is caused by mitral regurgitation due to loss of the sphincter action of the mitral annulus. Diagnosis is made by one- or two-dimensional echocardiography. Calcification in the mitral ring may be seen on chest x-ray films or fluoroscopy. Management includes antibiotic prophylaxis to avoid infective endocarditis and observation for the development of congestive heart failure. Conventional management with digitalis and diuretics is supplemented with use of vasodilators in severe cases.
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Papa et al. (1982) conducted a review in Mitral annular calcification. Mitral annular calcification predominantly affects females over 65 years of age, causes mitral regurgitation, and is managed with antibiotic prophylaxis, digitalis, diuretics, and vasodilators.
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