Key result
Low vaccination coverage was significantly associated with increased odds of a country reporting cVDPV (Adjusted OR 83.41; 95% CI 5.01-1387.71; p=0.0020).
Why the study?
Vaccine-derived poliovirus remains a major barrier to polio eradication, with concerning recent growing emergences.
Case-Control (n=1,818)
Yes
Odds Ratio: 83.41 (95% CI 5.01–1387.71)
p-value: p=0.0020
Low polio vaccination coverage is strongly associated with the emergence of circulating vaccine-derived poliovirus, highlighting the need for high vaccination rates globally.
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Lai et al. (2022) conducted a case-control in Circulating vaccine-derived poliovirus (cVDPV) (n=1,818). Low vaccination coverage vs. Higher vaccination coverage was evaluated on Reporting cVDPV (Adjusted OR 83.41, 95% CI 5.01-1387.71, p=0.0020). Low vaccination coverage was significantly associated with increased odds of a country reporting cVDPV (Adjusted OR 83.41; 95% CI 5.01-1387.71; p=0.0020).
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