Key result
Renal sympathetic denervation reduced systolic blood pressure by at least 20 mm Hg in six out of seven patients with severe refractory hypertension at six months post-procedure.
Why the study?
Does renal sympathetic denervation reduce blood pressure in patients with severe uncontrolled hypertension?
Observational (n=7)
No
Does renal sympathetic denervation reduce blood pressure in patients with severe uncontrolled hypertension?
Renal sympathetic denervation using the Symplicity catheter substantially reduced systolic blood pressure by at least 20 mm Hg in a small cohort of patients with severe, drug-resistant hypertension.
May support renal denervation in refractory hypertension; hypothesis-generating and requires randomized confirmation.
No abstract yet. The journal hasn't published one we can show.
No takes yet. Share an insight, caveat, or question.
Peregrín et al. (2016) conducted an observational in Severe idiopathic refractory hypertension (n=7). Renal sympathetic denervation was evaluated on Decrease in systolic blood pressure by at least 20 mm Hg at 6 months. Renal sympathetic denervation reduced systolic blood pressure by at least 20 mm Hg in six out of seven patients with severe refractory hypertension at six months post-procedure.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: