What is the clinical evidence from this study?

Study design: RCT. Population: Hypertension (n=150). Intervention: Overweight and obesity vs. Normal weight. Primary outcome: Blood pressure and lipid profile (TC, HDL-c, LDL-c, TG).

March 1, 2016Romanian Journal of Diabetes Nutrition and Metabolic Diseases1 citationsOpen Access

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The Impact of Anthropometric Measurements on Lipid Profile in Normal, Overweight and Obese Adults with Hypertension

KBKarima Bereksi-ReguigUniversité Djilali de Sidi Bel Abbès AMAissani Mira CIChenaoui IbrahimUniversité IBN Khaldoun Tiaret

Key Result

Overweight and obesity were significantly associated with increased blood pressure and altered total cholesterol and LDL-c levels compared to normal weight in hypertensive patients.

Study Design

Type

RCT (n=150)

Multicenter

Structured PICO

Does overweight and obesity worsen the lipid profile and blood pressure in hypertensive adults compared to normal weight?

Population

150 hypertensive patients aged 33-91 years, divided by body weight into normal weight versus overweight and obesity groups.

Intervention

Overweight and obesity (body weight category)

Comparator

Normal weight

Outcome

Blood pressure (systolic and diastolic) and lipid profile (total cholesterol, HDL-c, LDL-c, and triglycerides)surrogate

In hypertensive adults, being overweight or obese is associated with worse lipid profiles (higher total cholesterol and LDL-c) and higher blood pressure compared to having a normal weight.

Abstract

Abstract Background and Aims: We investigated the association of anthropometric measurements with lipid profile in adult hypertensive patients with normal weight and overweight including obesity. Materials and Method: This was a randomized study performed in Tiaret, Algeria, on 150 hypertensive patients aged 33-91 years. Patients were divided according to their body weight (normal weight vs. overweight and obesity) into two groups. Weight, height and body mass index (BMI) were measured to estimate the various categories of body weight. The blood pressure (systolic and diastolic) and lipid profile (total cholesterol (TC), high-density lipoprotein cholesterol (HDL-c), low-density lipoprotein cholesterol (LDL-c) and triglycerides (TG) were analyzed. Results: We found significant relations between body weight and blood pressure. Patients with normal weight had a normal blood pressure. However, a significant increase in blood pressure was observed in patients with overweight and obesity. Numerous significant relationship were disclosed for TC and LDL-c. Conclusion: Lipid profile is related with weight status in hypertensive overweight/obese patients.

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Cite This Study

Bereksi-Reguig et al. (Tue,) conducted a rct in Hypertension (n=150). Overweight and obesity vs. Normal weight was evaluated on Blood pressure and lipid profile (TC, HDL-c, LDL-c, TG). Overweight and obesity were significantly associated with increased blood pressure and altered total cholesterol and LDL-c levels compared to normal weight in hypertensive patients.

synapsesocial.com/papers/6a8e3c9c19c8d3d09b80567a https://doi.org/https://doi.org/10.1515/rjdnmd-2016-0006

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