Key result
Mechanical thrombectomy using the Penumbra Indigo Aspiration System and temporary IVC filter placement successfully treated acute pulmonary embolism in a 77-year-old female with active bleeding.
Why the study?
Clinical scenarios involving acute PE with contraindications to anticoagulation necessitate alternative therapeutic approaches.
Case Report (n=1)
Mechanical thrombectomy combined with an IVC filter offers a viable alternative for managing acute pulmonary embolism in frail patients with contraindications to anticoagulation.
This hypothesis-generating data supports alternative interventions for acute pulmonary embolism when anticoagulation is.
Venous thromboembolism (VTE), encompassing deep vein thrombosis (DVT) and pulmonary embolism (PE), are the leading causes of mortality and morbidity worldwide. Embolization of deep vein thrombi into the pulmonary arteries is thought to be the most common cause of PE. While the standard management of acute PE involves anticoagulation, mechanical thrombectomy, and, in certain cases, the use of inferior vena cava (IVC) filters, clinical scenarios with contraindications to anticoagulation necessitate alternative therapeutic approaches. We present the case of a 77-year-old female who presented with acute PE and multiple comorbidities, including active hematuria. The patient was successfully managed by mechanical thrombectomy using the Penumbra Indigo® Aspiration System (Penumbra Inc., Alameda, CA) and subsequently underwent temporary implantation of an IVC filter to prevent the risk of recurrence. This case contributes to advancing current knowledge in the management of acute PE, particularly in frail, elderly patients with multiple comorbidities, and reinforces the critical role of personalized, multi-modal therapeutic approaches in improving survival rates.
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Pande et al. (2025) conducted a case report in Acute pulmonary thromboembolism (n=1). Mechanical thrombectomy and temporary IVC filter was evaluated on Successful thrombus aspiration and clinical recovery. Mechanical thrombectomy using the Penumbra Indigo Aspiration System and temporary IVC filter placement successfully treated acute pulmonary embolism in a 77-year-old female with active bleeding.
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