Key result
The left atrial septal pouch (LASP) has a mixed association with cryptogenic stroke in initial epidemiologic studies, requiring further investigation to determine its clinical significance.
The clinical significance of the left atrial septal pouch in cryptogenic stroke remains uncertain and requires further investigation to guide potential interventions.
LASP should not yet inform cryptogenic stroke evaluation or management; leaves open its clinical relevance pending prospective studies.
The left atrial septal pouch (LASP) is an anatomic variant of the atrial septum that forms a blind-ending pouch, communicating exclusively with the left atrium (LA). Case reports have demonstrated thrombus within LASP and in the setting of cryptogenic stroke. Initial epidemiologic results are mixed, one study showing and others not showing an association between LASP and cryptogenic stroke. Additional investigation should take place to determine the clinical significance of LASP and what interventions are required to prevent ischemic stroke in at-risk individuals.
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Wong et al. (2015) conducted a review in Cryptogenic stroke. Left atrial septal pouch (LASP) was evaluated on Cryptogenic stroke. The left atrial septal pouch (LASP) has a mixed association with cryptogenic stroke in initial epidemiologic studies, requiring further investigation to determine its clinical significance.
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