Intravascular papillary endothelial hyperplasia of bone can present with high metabolism on bone scan and PET/CT, mimicking malignancy, and awareness can prevent unnecessary invasive treatments.
Awareness of high uptake in intravascular papillary endothelial hyperplasia may prevent misdiagnosis as malignancy; extends the differential for hypermetabolic bone lesions.
Multiple intravascular papillary endothelial hyperplasia involved with bone is rare. In this study, we present the case of a 53-year-old woman having occasional chest pains located in the middle of the sternum and the left chest wall. Multiple intravascular papillary endothelial hyperplasia lesions with high metabolism distributed in the sternum, left ribs, 12th thoracic vertebra, and left ilium on bone scintigraphy as well as PET/CT, which were easily misdiagnosed as bone malignant tumors. Increased awareness of this benign lesion and its high metabolic findings will improve preoperative diagnosis and avoid misinterpretation that may lead to an unnecessary invasive treatment.
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Tang et al. (2018) studied this question.
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