Key result
Subacute sclerosing panencephalitis presents with atypical symmetric putaminal diffusion restriction and frontal white matter changes.
Case Report (n=1)
Subacute sclerosing panencephalitis can present with an atypical MRI pattern of symmetric putaminal diffusion restriction, emphasizing the importance of clinical and EEG correlation.
Expands the recognized neuroimaging spectrum of subacute sclerosing panencephalitis to include basal ganglia involvement.
Subacute sclerosing panencephalitis (SSPE) classically shows parieto-occipital white matter changes on magnetic resonance imaging (MRI). We report an 11-year-old boy with prior measles infection presenting with neuroregression and myoclonus, with electroencephalography (EEG) showing periodic complexes. MRI revealed atypical symmetric putaminal diffusion restriction with frontal white matter changes. Diagnosis was confirmed by elevated cerebrospinal fluid anti-measles IgG. This case highlights an atypical imaging pattern of SSPE, emphasizing the importance of clinical and EEG correlation for early diagnosis.
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Arbujin et al. (2026) conducted a case report in Subacute sclerosing panencephalitis (SSPE) (n=1). Magnetic resonance imaging (MRI) was evaluated on Neuroimaging pattern. An 11-year-old boy with subacute sclerosing panencephalitis presented with an atypical neuroimaging pattern of symmetric putaminal diffusion restriction and frontal white matter changes.
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