Systematic review evaluates catalytic oxidation routes for benzaldehyde synthesis, highlighting sustainable pathways using molecular oxygen and key scalability challenges.
Key Points
To critically review catalytic oxidation pathways for benzaldehyde production, focusing on benzyl alcohol and toluene oxidation while evaluating green synthetic alternatives and scalability challenges.
Systematically analyzed reaction conditions, catalyst performance descriptors (conversion and selectivity), and reaction phases across diverse heterogeneous and homogeneous systems.
Compared conventional synthetic routes against green oxidation methodologies utilizing molecular oxygen or air.
Operating temperature, reaction phase, and oxidant choice emerged as the primary determinants of product distribution and conversion efficiency.
Molecular oxygen and air demonstrated superior sustainability by reducing energy demands and eliminating hazardous stoichiometric waste.
Catalyst deactivation, overoxidation to unwanted by-products, and scale-up constraints were identified as the main scientific barriers hindering large-scale heterogeneous adoption.
Cite This Study
Bedoya-Betancur et al. (2026) studied this question.