Why the study?
Environmental factors and gene-environment interactions also lead to non-syndromic congenital heart disease, creating a need to integrate non-genetic and genetic information into a single platform.
Population
Over 4200 manually curated records from PubMed associated with NS-CHD
Design
Knowledge base curation and functional analysis
Authors
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Provides a centralized resource for evaluating multifactorial congenital heart disease risks; extends current genetic.
The CHD-RF-KB database provides a centralized, curated platform for clinicians and researchers to evaluate genetic and environmental risk factors for non-syndromic congenital heart disease.
Yang et al. (2021) studied this question.
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