Why the study?
Does dexmedetomidine-based opioid-free anesthesia improve hemodynamic stability and reduce postoperative pain compared to fentanyl-based anesthesia in patients undergoing elective laparoscopic cholecystectomy?
Population
80 patients scheduled for elective laparoscopic cholecystectomy
Comparison
Dexmedetomidine and propofol vs Fentanyl and propofol
Design
RCT, randomly divided into two equal groups
Follow-up
perioperative and postoperative period
Authors
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Dexmedetomidine improves intraoperative hemodynamic stability versus fentanyl in laparoscopic cholecystectomy; extends RCT support for opioid-free anesthesia.
Does dexmedetomidine-based opioid-free anesthesia improve hemodynamic stability and reduce postoperative pain compared to fentanyl-based anesthesia in patients undergoing elective laparoscopic cholecystectomy?
Dexmedetomidine-based opioid-free anesthesia provides better intraoperative hemodynamic stability and postoperative analgesia compared to fentanyl in patients undergoing laparoscopic cholecystectomy.
Shalaby et al. (2018) studied this question.
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