Why the study?
Does mivazerol reduce hemodynamic instability and the need for cardiovascular medications in patients with coronary artery disease undergoing vascular surgery?
Population
317 patients aged ≥21 years with coronary artery disease and normal renal function undergoing vascular…
Comparison
Mivazerol (one of two doses) vs Placebo
Design
RCT, block randomization within each center, double-blind, placebo-controlled
Follow-up
72 hours postoperatively
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Mivazerol reduces perioperative tachycardia, hypertension, and ischemia treatment needs in CAD vascular surgery patients; confirms alpha2-agonist sympatholysis in this RCT.
Does mivazerol reduce hemodynamic instability and the need for cardiovascular medications in patients with coronary artery disease undergoing vascular surgery?
A 1997 study studied this question.
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