Key result
Mitral repair is the optimal treatment for degenerative mitral regurgitation, yet US repair rates remain at 60-80% despite the established inferiority of replacement.
Why the study?
Many patients with degenerative mitral regurgitation are referred too late for optimal outcomes, and US repair vs replacement rates remain low despite known inferiority of replacement.
Mitral repair is the optimal treatment for degenerative mitral regurgitation, requiring timely referral and utilization of advanced repair techniques to improve outcomes.
PURPOSE OF REVIEW: Mitral repair is the best treatment for degenerative mitral regurgitation. Many patients are referred too late for optimal outcomes. The US repair vs. replacement rate is only 60-80%, at a time when the inferiority of replacement has been established. Therefore, widely used traditional techniques of repair are being reappraised. RECENT FINDINGS: Identification of risk factors predictive of poor early and late outcome have improved timing for surgical referral. Composite risk scores have been developed. Novel echocardiographic, cardiac MRI, and molecular level risk factors could improve timing. Analysis of factors contributing to low repair rates is also of critical importance. The role of institutional and surgeon volumes have been identified. More detailed data on the importance of dynamic function of the mitral valve have led to improved repair techniques such as intraoperative simulation of end diastole and early systole, use of expanded polytetrafluoroethylene neochords instead of leaflet resection, and dynamic instead of rigid annuloplasty. SUMMARY: Our perception of mitral regurgitation has changed from a seemingly simple condition to one of considerable complexity at multiple levels. National guidelines should be studied and followed.
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Gerald M. Lawrie (2020) conducted a review in Mitral regurgitation. Mitral repair vs. Mitral replacement was evaluated. Mitral repair is the optimal treatment for degenerative mitral regurgitation, yet US repair rates remain at 60-80% despite the established inferiority of replacement.
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