Why the study?
Severe primary mitral regurgitation has poor outcomes if uncorrected, and despite mitral valve repair being superior to replacement, repair is underutilized and many patients receive replacement unnecessarily.
Highlights the superiority of mitral valve repair over replacement for severe primary MR and advocates for referral to specialized surgeons to optimize outcomes.
May favor repair over replacement by experienced teams in severe primary MR; leaves open need for contemporary randomized confirmation.
Severe primary mitral regurgitation (MR) has a poor outcome if left uncorrected. Successful mitral valve repair has the unique potential to restore normal life expectancy and is superior to valve replacement. Despite this, mitral repair is performed relatively infrequently and many patients with potentially reparable valves have a replacement instead, subjecting them to unnecessary risk. Surgery in asymptomatic patients is a particularly difficult issue with some units advocating surgery irrespective of symptoms, based purely on the severity of regurgitation. This strategy cannot be widely adopted with the current patchy provision of high-quality valve repair surgery. Misplaced enthusiasm for early operation runs the risk of a failed repair and the hazards of a mechanical prosthesis. To ensure optimal treatment for patients with MR, cardiologists must be aware of the indications for valve repair and ensure that patients with potentially reparable valves are referred to surgeons with proven expertise, even if this means a shift from established practice. Surgical units need to promote subspecialization and rigorously audit their outcomes. There are currently no agreed standards for best practice in mitral valve repair and this is an area where professional societies may wish to take a role.
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Ray et al. (2006) studied this question.
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