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February 1, 1996Neurology

Brain damage and postoperative hyponatremia

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Key result

Postoperative hyponatremia occurs in 1% to 5% of patients and can lead to death or permanent brain damage following elective surgery, particularly in menstruant women.

Population

Generally healthy individuals who have recently had elective surgery, with a propensity in menstruant women

Design

Review

Authors

JAJuan Carlos AyusUniversity of California, IrvineAAAllen I. ArieffUniversity of Southern California

Discussion

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Implication

Requires vigilant postoperative sodium monitoring in menstruant women; leaves open optimal prevention strategies in prospective trials.

Structured PICO

P
Population
Generally healthy individuals who have recently had elective surgery, with a propensity in menstruant women
O
Outcome
Death or permanent brain damagehard clinical

Highlights the risk of death or permanent brain damage from postoperative hyponatremia, especially in menstruant women following elective surgery.

Limitations

  • Epidemiologic data are difficult to acquire for a sporadic condition that affects hospitalized patients, so the frequency of permanent brain damage is not generally known.

Cite This Study

Ayus et al. (1996) conducted a review in Postoperative hyponatremia. Postoperative hyponatremia was evaluated on Death or permanent brain damage. Postoperative hyponatremia occurs in 1% to 5% of patients and can lead to death or permanent brain damage following elective surgery, particularly in menstruant women.

synapsesocial.com/papers/6a8ee47f96767b15a7fffc81https://doi.org/10.1212/wnl.46.2.323
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