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Hadron masses show a specific dependence on the quark masses. Therefore, the variation of these masses can cause a resonance in a hadronic scattering amplitude to become a bound state. Consequently, the amplitude exhibits a non-analytic behavior at this transition. Crossed amplitudes, where the resonance can be exchanged in the t-channel, can be shown to exhibit the same phenomenon by s→t analytic continuation. This entails possible kinks in lattice quark-mass extrapolations needed to compute hadronic observables.
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Guo et al. (2011) studied this question.
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