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A new synthesis of phthalazine has been effected by reduction of the commercially available 1‐hydrazinophthalazine hydrochloride. The preparation of quinazoline in three steps from anthranilic acid on a large laboratory scale is described. It is believed that these are the most convenient syntheses available for phthalazine and quinazoline.
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Wilfred L.F. Armarego (1961) studied this question.
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