Key result
Infant atrial septal defects diagnosed before 3 months spontaneously close in ~87% of cases.
Population
101 infants with an interatrial shunt diagnosed before age 3 months and confirmed by Doppler echocardiography
Design
Cohort
Follow-up
average 265 +/- 190 days
Authors
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Atrial septal defects <8 mm diagnosed in the first 3 months of life have a high rate of spontaneous closure, whereas those ≥8 mm are unlikely to close spontaneously and may require surgical correction.
Cohort (n=101)
Atrial septal defects <8 mm diagnosed in the first 3 months of life have a high rate of spontaneous closure, whereas those ≥8 mm are unlikely to close spontaneously and may require surgical correction.
Journal, society, and media accounts. Useful signal, not independent expert judgment.
Radzik et al. (1993) conducted a cohort in Atrial septal defects (n=101). Initial atrial septal defect diameter was evaluated on Spontaneous closure of atrial septal defects. Spontaneous closure of atrial septal defects diagnosed before 3 months of age occurred in 87% of infants, with closure rates of 100% for defects <3 mm, 87% for 3-5 mm, and 80% for 5-8 mm.
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