Key result
Echovirus 22 virion RNA resists digestion by certain nucleases and resolves into two species upon shearing, suggesting a linear RNA molecule with a 5' hairpin structure.
Population
Echovirus 22 virion RNA
Comparison
Phenol extraction, digestion with pancreatic… vs Poliovirus virion RNA
Design
Preclinical
Authors
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Distinguishes echovirus RNA from poliovirus; leaves open therapeutic targeting of 5' hairpins in enteroviruses.
Echovirus 22 virion RNA contains a double-stranded or base-paired region, likely a 5' hairpin, distinguishing it from poliovirus RNA.
Seal et al. (1984) studied Echovirus 22. Echovirus 22 virion RNA resists digestion by certain nucleases and resolves into two species upon shearing, suggesting a linear RNA molecule with a 5' hairpin structure.
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