Key result
ECHO viruses types 22 and 23 demonstrated distinctive cytopathology compared to other enteroviruses, characterized by the eventual disappearance of the nucleolus and nuclear chromatin.
Population
Tissue culture infected with ECHO viruses types 22 and 23 (including 7 isolates of ECHO 22)
Comparison
Infection with ECHO viruses types 22 and 23 vs Other enteroviruses
Design
Preclinical
Authors
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May aid enterovirus classification in culture; leaves open clinical diagnostic translation.
ECHO viruses types 22 and 23 exhibit distinctive nuclear cytopathology in tissue culture, which may help in classifying new viral agents.
Shaver et al. (1961) studied ECHO Viruses Types 22 and 23 (in vitro). ECHO Viruses Types 22 and 23 vs. Other enteroviruses was evaluated on Cytopathology. ECHO viruses types 22 and 23 demonstrated distinctive cytopathology compared to other enteroviruses, characterized by the eventual disappearance of the nucleolus and nuclear chromatin.
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