Key result
EV22 neutralizing antibodies were highly prevalent in neonates (95%) and adults (97%), but low in children aged 2-12 months (20%), demonstrating rapid acquisition of antibodies with age.
Cross-Sectional (n=250)
Yes
Echovirus 22 antibodies are highly prevalent in neonates (likely maternal) and adults, with infections most commonly presenting as gastroenteritis and respiratory symptoms.
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High EV22 seroprevalence in neonates/adults but low in young infants suggests early susceptibility window; leaves open prospective studies on infection risk.
Joki‐Korpela et al. (1998) conducted a cross-sectional in Echovirus 22 infection (n=250). Echovirus 22 was evaluated on EV22 seroprevalence across age groups. EV22 neutralizing antibodies were highly prevalent in neonates (95%) and adults (97%), but low in children aged 2-12 months (20%), demonstrating rapid acquisition of antibodies with age.
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