Key result
Recent literature on myopathies highlights the reclassification of polymyositis, diagnostic challenges in sporadic late-onset nemaline myopathy, and treatments for nondystrophic channelopathies.
This review highlights recent literature on inflammatory myopathies, including subclinical cardiac involvement and immune checkpoint inhibitor myositis, as well as nemaline myopathy and nondystrophic channelopathies.
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Monoclonal gammopathy screening in sporadic late-onset nemaline myopathy may warrant consideration; leaves open prospective validation of clinical impact.
This edition concentrates on inflammatory myopathies with reports of reclassification of polymyositis, cancer associations, evaluation of subclinical cardiac involvement, myositis-specific and -associated antibodies, and immune checkpoint inhibitor myositis. A number of reports address sporadic late-onset nemaline myopathy and point out its diagnostic difficulty and the importance of identifying an associated monoclonal gammopathy that is likely of clinical significance and may warrant aggressive immunotherapy. Finally, treatment of nondystrophic channelopathies is addressed.
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A 2021 study conducted a review in Myopathy. Recent literature on myopathies highlights the reclassification of polymyositis, diagnostic challenges in sporadic late-onset nemaline myopathy, and treatments for nondystrophic channelopathies.
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