Review of trials reveals adoption patterns of patient-reported outcomes in acute stroke clinical trials, highlighting a need for patient-centered recovery metrics.
Patient-reported outcome measures (PROMs) capture patient-centered recovery domains that may be missed by traditional functional end points. We evaluated the adoption of PROMs and trial-level factors associated with PROM reporting in phase II–III randomized controlled trials (RCTs) of acute stroke published between 1995 and 2025.
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Ali et al. (2026) studied this question.
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