Whole-body magnetic resonance imaging (MRI) or computed tomography (CT) screening for reducing morbidity and mortality from multiple diseases in asymptomatic adults

Ziheng Chen; Minna Johansson; Loai Albarqouni; Steven Woloshin; Karsten Juhl Jørgensen

doi:10.1002/14651858.cd016234

August 25, 2026Cochrane library

Whole-body magnetic resonance imaging (MRI) or computed tomography (CT) screening for reducing morbidity and mortality from multiple diseases in asymptomatic adults

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Key Points

To outline the protocol for evaluating the benefits and harms of whole-body MRI or CT screening in asymptomatic adults compared to usual care, no screening, or non-whole-body screening strategies.
Protocol for a Cochrane systematic review of interventions evaluating whole-body imaging.
Compares asymptomatic adults receiving whole-body MRI or CT screening against those receiving no intervention, standard care, or alternative screening modalities.
This publication represents a study protocol; primary outcome data, effect estimates, and event rates are not yet collected or reported.
The completed review will synthesize clinical trial evidence on morbidity, all-cause and disease-specific mortality, and potential screening-related harms.

Implication

Systematic review protocol outlines methods to evaluate whole-body MRI or CT screening in asymptomatic adults, highlighting the evidence gap in routine full-body imaging.

Abstract

OBJECTIVES: This is a protocol for a Cochrane review (intervention). The objectives are as follows: To evaluate the benefits and harms of whole-body magnetic resonance imaging (MRI) or computed tomography (CT) scans for screening in asymptomatic adults, compared with no intervention, usual care, or alternative screening strategies not involving whole-body MRI or whole-body CT.

Discussion

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Cite This Study

Chen et al. (2026) studied this question.

synapsesocial.com/papers/6a8fe98110c91c1e92621241 https://doi.org/10.1002/14651858.cd016234

View Full Paper

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Whole-body magnetic resonance imaging (MRI) or computed tomography (CT) screening for reducing morbidity and mortality from multiple diseases in asymptomatic adults

Key Points

Implication

Abstract

Discussion

Cite This Study

Whole-body magnetic resonance imaging (MRI) or computed tomography (CT) screening for reducing morbidity and mortality from multiple diseases in asymptomatic adults

Key Points

Implication

Abstract

Discussion

Cite This Study

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