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August 27, 2026Journal of the korean society of manufacturing technology engineersOpen Access

Automated Pupil Center Tacking Method and Autofocusing Algorithm for Fundus Image Acquisition

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Authors

YKYongsang KimMCMin-June ChoKKKihyun Kım

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Overview

Experimental validation demonstrates real-time pupil tracking and rapid autofocusing in a portable fundus camera system, highlighting improved accessibility for retinal disease screening.

Key Points

  • Develop an automated pupil tracking and autofocusing system using a compact fundus camera to enable reliable retinal disease screening in teleophthalmology.
  • Integrated a portable fundus camera, a motorized stage, and a processing computer into an automated prototype.
  • Implemented real-time pupil center localization using a YOLO-based bounding box detector.
  • Conducted autofocusing via infrared image sharpness metrics combined with moving average smoothing and open-loop motorized stage control.
  • Achieved an operational control speed of 15 frames per second.
  • Attained an optical axis alignment error of approximately 22 pixels (~121 μm).
  • Produced final white-light fundus images with only 1.7% metric degradation compared to ideal focus conditions.

Cite This Study

Kim et al. (2026) studied this question.

synapsesocial.com/papers/6a8fe9da10c91c1e92621d2ehttps://doi.org/10.7735/ksmte.2026.35.4.300
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Compact Fundus Imaging System Using Shack-Hartmann Wavefront Sensing for High-speed Auto-focus2026
  2. 2A Miniaturized Large-Field Fundus Optical System Based on Aspheric Imaging and Non-Coaxial Illumination2024 · 1 citations
  3. 3In vivo fundus imaging and computational refocusing with a diffuser-based fundus camera2024
  4. 4Active Gaze Guidance and Pupil Dilation Effects Through Subject Engagement in Ophthalmic Imaging2025 · 1 citations
  5. 5Robust autofocus method based on patterned active illumination and image cross-correlation analysis2024 · 2 citations