What does this research mean for the field?

Uncertainty in illness is positively correlated with depression and anxiety in patients with Systemic Lupus Erythematosus, increasing their risk for these psychological symptoms. Novelty: ClaimNovelty.CONFIRMATORY. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To examine the relationship between illness uncertainty and psychological adjustment among individuals diagnosed with systemic lupus erythematosus.

August 27, 2026Lupus

Uncertainty in illness and psychological adjustment in patients with systemic lupus erythematosus

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Authors

TSTheresa SkojecMedical University of South Carolina TDTatiana M. DavidsonMedical University of South Carolina TKTeresa J. KelechiMedical University of South Carolina

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Implication

Cross-sectional study finds illness uncertainty positively correlates with depression and anxiety in systemic lupus erythematosus, highlighting the need for routine mental health screening.

Key Points

To examine the relationship between illness uncertainty and psychological adjustment among individuals diagnosed with systemic lupus erythematosus.
Conducted a cross-sectional descriptive survey using an anonymous online questionnaire battery.
Assessed illness uncertainty, psychological adjustment, quality of life, and social determinants of health factors.
Illness uncertainty correlated positively with symptoms of depression.
Illness uncertainty correlated positively with symptoms of anxiety, indicating poorer overall psychological adjustment to chronic disease.

Cite This Study

Skojec et al. (2026) studied this question.

synapsesocial.com/papers/6a8fea0110c91c1e92621fa3 https://doi.org/10.1177/09612033261484790

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Implication

Cross-sectional study finds illness uncertainty positively correlates with depression and anxiety in systemic lupus erythematosus, highlighting the need for routine mental health screening.

Uncertainty in illness and psychological adjustment in patients with systemic lupus erythematosus

Discussion

Member takes

Implication

Key Points

Cite This Study

Uncertainty in illness and psychological adjustment in patients with systemic lupus erythematosus

Discussion

Member takes

Implication

Key Points

Cite This Study

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